Severe bacterial infections in people who inject drugs: the role of injection-related tissue damage Full Text

Always try to inject at least one inch “up” from your previous injection site . In the past hepatitis C treatment was largely ineffective and had serious side effects. Since 2013, there iv drug use have been highly effective, all-oral, cures for hepatitis C. However, it may be difficult to access treatment based on where you live, your medical coverage, and your liver damage.

  • Therefore, we used broad-spectrum anti-fungals and achieved moderate success.
  • Sometimes injection drug use is diagnosed when people go to a health care practitioner because they want help stopping use of the drug.
  • Reduce your chance of getting a serious illness by using clean needles and equipment and cleaning your skin before you inject.
  • This is particularly common with users who have been injecting while in jail and re-use disposable syringes sometimes hundreds of times.

Misusing any medication or drug is dangerous and can result in an overdose. However, one of the most severe health dangers of IV drug use is that it significantly increases the risk of overdosing and death. IV drug use introduces a drug directly to the bloodstream, heightening and intensifying its effects. When a virus, bacteria or other germs are introduced and trapped beneath the skin, an abscess can form. Local infection in the skin results in the body’s immune system trying to defend itself from the infection by sending white blood cells to the infected area.

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For this reason, the most experience, careful intravenous drug user is also apt to explore new injection sites. Self-treatment of abscesses by PWID is common and may lead to the development of SBI. Localized SSTI as a result of injection practices was a recurring theme and perceived to be manageable without seeking medical attention. Perceptions regarding risk, anecdotal experience with self-treatment, as well as physical factors including one’s addiction may explain reluctance to seek medical care. Additionally, prior negative experiences within the context of inadequate opioid withdrawal management may also lead to reluctance to seek medical treatment . Sharing of other drug injection equipment, including cottons/filters, cookers, and drug diluting water and/or containers, was more commonly reported among participants and perceived as less risky.

  • Imaging primarily plays a role where a complication of cellulitis, such as a soft tissue abscess or deep venous thrombosis, is suspected.
  • An antitoxin is needed to stop the negative effects of the toxin in your body to treat wound botulism.
  • While any form of injection drug use is risky, injecting into an artery is even riskier.
  • If thrombin injection is unsuccessful or the neck is too wide, angiographic placement of a stent or surgery may be necessary .

Imaging primarily plays a role where a complication of cellulitis, such as a soft tissue abscess or deep venous thrombosis, is suspected. However, imaging should be considered in all patients with a confirmed history or considerable clinical suspicion of injected drug use due to their higher risk of complications. Soft tissue abscess may develop locally at site of injection or extend to deeper locations due to direct of haematogenous spread.

Long-Term Damage to the Nervous System

In addition to the risk of rupture, mycotic aneurysms may also lead to the development of arteriovenous fistulae or serve as a source of sepsis or septic emboli . Radiographic findings in acute osteomyelitis include periosteal reaction (Fig. 9), regional osteopenia, cortical erosion, endosteal scalloping and overlying soft tissue swelling or deformity . CT findings are similar to those on plain radiographs and include soft tissue swelling, regional osteopenia and cortical erosions. While CT provides greater sensitivity than plain radiographs and is the imaging modality of choice for assessment of osseous erosions, it cannot reliably identify bone oedema early in the disease process .

Research has shown that bacterial and fungal infections are increasing among people who inject drugs. Complex regional pain syndrome type II at the right foot may explain the presence of pain, although heroin withdrawal symptoms may have contributed. With complex regional pain syndrome type II diagnosis, pregabalin 75 mg bid per day was prescribed and an intensive pain relief was achieved. Pregabalin has been shown to be effective in the treatment of pain as one of heroin withdrawal symptoms; however, when it is used with heroin at the same time, it enhances the effects of heroin and increases the risk of overdose. Our patient quitted drug addiction and, therefore, we were able to use pregabalin. Injection drug users have unique challenges because of additional social stigma, substantially increased risk for infectious diseases, the health consequences of injection drug use, and the addiction to the injection process itself.

Prevention[edit | edit source]

Patients may be more likely to disclose their illicit drug use with a therapist whom they trust. While injecting drugs is already incredibly risky, these three injection sites should never be used under any circumstances. Abstinence coupled with appropriate counseling can alleviate most mental health symptoms. Appropriate medical care can improve weakened immune systems and treat or monitor medical complications that arose as a result of drug use.

To minimize the amount of undissolved material in fluids prepared for injection, a filter of cotton or synthetic fiber is typically used, such as a cotton-swab tip or a small piece https://ecosoberhouse.com/ of cigarette filter. Swallowing tends to be the safest and slowest method of ingesting drugs. It is safer as the body has a much greater chance to filter out impurities.

ExcludeTraining GuideGetting Off Right: A Safety Manual for Injection Drug Users

Many of these conditions can be treated, especially once drug use is stopped. Mental health issues, such as depression and anxiety, are very common in people with extended drug use. Short-term effects of recreational drugs on the nervous system vary according to the type of drug. The pleasure centers of the brain, which receive neurotransmitters like dopamine, are affected by drugs of abuse, no matter which type of drug they are.

nerve damage from iv drug use

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